Epigenetic programming of hypoxic–ischemic encephalopathy in response to fetal hypoxia
نویسندگان
چکیده
منابع مشابه
Fetal epigenetic programming of adipokines
Epigenetics generates a considerable interest in the field of research on complex traits, including obesity and diabetes. Recently, we reported a number of epipolymorphisms in the placental leptin and adiponectin genes associated with maternal hyperglycemia during pregnancy. Our results suggest that DNA methylation could partly explain the link between early exposure to a detrimental fetal envi...
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How the fetus withstands an environment of reduced oxygenation during life in the womb has been a vibrant area of research since this field was introduced by Joseph Barcroft, a century ago. Studies spanning five decades have since used the chronically instrumented fetal sheep preparation to investigate the fetal compensatory responses to hypoxia. This defence is contingent on the fetal cardiova...
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The incidence of obesity and overweight has reached epidemic levels in the United States and developed countries worldwide. Even more alarming is the increasing prevalence of metabolic diseases in younger children and adolescents. Infants born to obese, overweight, and diabetic mothers (even when normal weight) have increased adiposity and are at increased risk of later metabolic disease. In ad...
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ژورنال
عنوان ژورنال: Progress in Neurobiology
سال: 2015
ISSN: 0301-0082
DOI: 10.1016/j.pneurobio.2014.11.001